May 26th, 2009 
My Health 
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I bought some coenzyme q10 based upon the recommendation of my opthomologist (my multiple cardiac arrests had affected my vision). However, my cardiologist and endocrinologist (yes, I was that messed up), tell me that initial reports on coenzyme q10 were very promising, but that recently (within last year) the consensus is that it has no value (though no damaging effect). Does anyone have recent info based on recent studies that show if this medicine is effective? Thanks.
Start at http://www.lef.org/ and search for coq10 or search for ubiquinone or ubiquinol. Some good articles with many references will pop up.
Also, there is no “initial reports” but an ongoing list of solid research showing benefit in many areas. There is no “consensus” that it has no value and the alleged recent studies your doctors report to know about they should provide. I call it medical lying.
If you go to PubMed, a government site that provides medical abstracts for public use:
and do a search for medical abstracts using “ubiquinone OR ubiquinol” as the search term (the two forms of CoQ10), you will get 8367 medical abstracts. If you go to the advanced search and restrict this to human
only studies, you can cut down the number of abstracts to 2415.
Here’s one study published in 2008 that indicates your doctors are full of BS – there are related abstracts on the right on the PubMed pages one can examine:
http://www.ncbi.nlm.nih.gov/pubmed/19096107
Supplemental ubiquinol in patients with advanced congestive heart failure. Langsjoen PH, Langsjoen AM.
East Texas Medical Center and Trinity Mother Francis Hospital, TX, USA. alilangsjoen@cs.com
Patients with CHF, NYHA class IV, often fail to achieve adequate plasma CoQ10 levels on supplemental ubiquinone at dosages up to 900 mg/day. These patients often have plasma total CoQ10 levels of less than 2.5 microg/ml and have limited clinical improvement. It is postulated that the intestinal edema in these critically ill patients may impair CoQ10 absorption. We identified seven patients with advanced CHF (mean EF 22%) with sub-therapeutic plasma CoQ10 levels with mean level of 1.6 microg/ml on an average dose of 450 mg of ubiquinone daily (150-600 mg/day). All seven of these patients were changed to an average of 580
mg/day of ubiquinol (450-900 mg/day) with follow-up plasma CoQ10 levels, clinical status, and EF measurements by echocardiography. Mean plasma CoQ10 levels increased from 1.6 microg/ml (0.9-2.0 microg/ml) up to 6.5 microg/ml (2.6-9.3 microg/ml). Mean EF improved from 22% (10-35%) up to
39% (10-60%) and clinical improvement has been remarkable with NYHA class improving from a mean of IV to a mean of II (I to III). Ubiquinol has dramatically improved absorption in patients with severe heart
failure and the improvement in plasma CoQ10 levels is correlated with both clinical improvement and improvement in measurement of left ventricular function.
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Also, you should know that if you are taking a statin drug, your CoQ10 levels are being lowered. The outcome of lowered CoQ10 levels is an increase in sudden cardiac failure since CoQ10 is essential to energy
use in the heart.
As to endocrinologists, I’m a member of several hormone related lists including thyroid, adrenal, and testosterone replacement and of more than 10,000 members across the lists, there has only been one report of a positive experience with an endocrinologist and that person had no idea he had been screwed. Many had seem multiple endocrinologists over the years and ended up educating their own regular physician, often a Doctor with D.O. designation, in order to get appropriate and effective care. Most endocrinologist don’t even follow the recommendations of the Association of endocrinologists nor do they know what it recommends.
The Association is often wrong but is more correct that what a typical endocrinologist recommends. Adrenal fatigue, thyroid resistance, and high estrogen (in males) are three areas that endocrinologists have no clue about. Who knows how they are screwing diabetics?
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